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Automated Bioinformatics Pipelines
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- Added September 6, 2026
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[](https://www.skillsdirectory.com/skills/swaruplab-automated-bioinformatics-pipelines)---
name: automated-bioinformatics-pipelines
display_name: "Automated Bioinformatics Pipelines"
description: Pipeline maestro
keywords:
- workflows
- RNAseq
- ChIPseq
- automation
- YAML
measurable_outcome: Execute a configured pipeline end-to-end (including QC report + summary) within 24 hours of receiving inputs, logging every tool/parameter.
license: MIT
metadata:
author: BioMaster Team
version: "1.0.0"
compatibility:
- system: Python 3.9+
allowed-tools:
- run_shell_command
- read_file
---
# BioMaster Workflows
Orchestrate BioMaster’s multi-agent pipelines (RNA-seq, ChIP-seq, single-cell, Hi-C) using the provided configs and repos to deliver reproducible outputs.
## Workflow
1. **Config prep:** Populate YAML with tool paths, reference genomes, and workflow selection (`rnaseq`, `chipseq`, `singlecell`, `hic`).
2. **Environment:** `cd repo && pip install -r requirements.txt` (or container) prior to running.
3. **Launch:** `python repo/run.py --config repo/config.yaml` (or chosen config) and monitor progress.
4. **Error recovery:** Let BioMaster agents retry failing stages; review logs for missing reference/index files.
5. **Output packaging:** Collect BAMs/counts/peaks + QC + narrative summary of parameters and runtimes.
## Guardrails
- Fail fast when reference files or indices are absent to avoid wasted compute.
- Record tool versions for every stage (alignment, quantification, etc.).
- Require confirmation before deleting intermediates or rerunning destructive steps.
## References
- Full workflow descriptions, supported modalities, and repo links reside in `README.md`.
Files in this skill
- README.md
- SKILL.md
- repo/.readthedocs.yaml
- repo/README.md
- repo/agents/Biomaster.py
- repo/agents/CheckAgent.py
- repo/agents/Knowledge.py
- repo/agents/ToolAgent.py
- repo/agents/__init__.py
- repo/agents/ollama.py
- repo/agents/prompts.py
- repo/agents/utils.py
- repo/config.yaml
- repo/data/README.md
- repo/data/TruSeq3-PE.fa
- repo/docs/Makefile
- repo/docs/make.bat
- repo/docs/requirements.txt
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